Ilosone for otitis, pharyngitis, tonsillitis and other respiratory tract infections

otitisIlosone is indicated to treat acute otitis media (caused by Haemophilus influenza) in pediatric patients. The medication is combined with ethylsuccinate and sulfisoxazole acetyl to produce the most effect. The medication is preferred to be used in patients hypersensitive to penicillin.
The treatment of pharyngitis and tonsillitis (caused by S. pyogenes) with Ilosone is aimed to eradicate the microorganism from the nasopharynx.
Erythromycin (as alternative to other antibiotics) is chosen for treatment of streptococcal pharyngitis in patients hypersensitive to penicillin.
Erythromycin is effectively used for the treatment of respiratory tract infections caused by susceptible S. pneumonia, Mycoplasma pneumoniae or C. pneumonia.

How to use the erythromycin in the proper way?


This article will give you information on the proper use of drugs containing erythromycin. It may not be specific to Ilosone. You should read it carefully.

As the pharmacists prescribe erythromycins should be taken on an empty stomach washed down by a full glass of water (at least 1 hour before eating or 2 hours after you have eaten). If you have indigestion, you may take the drug within the meal. If you have any doubts of taking erythromycin you recommend you to speak with your individual physician.

It is possible to cure with oral liquid form of this drug:

  • The patient should take the drug by mouth even the drug is in a drop dispenser. If the drug does not come in a drop dispenser, a measuring spoon with special marks or other device of liquid drug measuring should be used to take the prescribed dose properly. The common house teaspoon may not measure the accurate amount of drug.
  • You should never use the drug when it is expired (please look at the date of the drug label) as the drug may not cure you in a proper way after the expiration date. Consult with your personal physician if you have any questions or doubts.

There are some recommendations for patients who prefer to use the chewable tablets of erythromycin:

  • You should crush or chew the tablets and then swallow them.

The drug has also a delayed-release form of with enteric-coated capsules or tablets:

  • The patient should not chew but only swallow capsules or tablets whole. This form of drug should not be broken or crushed. To be sure what form of erythromycin capsule or tablet you are prescribed for please contact your personal physician.

General information about Dosing

ilosoneThe dose of Ilosone in this class will be different for different people. The patient must follow the directions on the label or the doctor’s orders.  The amount of medicine that you take depends on the strength of the medicine. Also,  the time allowed between doses, the number of doses you take each day,and the length of time you take Ilosone depend on the medical problem for which patient is using the medicine.

If the patient missed the dose, he must take Ilosone as soon as possible. He doesn’t double doses. But, if it is almost time for his next dose of this drug, he must skip the tablet and go back to his regular dosing schedule.

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Side effects


Along with Ilosone needed effects, a drug may cause some unwanted effects.
Here we write all possible side effects:

Less common

Fever nausea
stomach pain (severe)
redness, skin rash, or itching
yellow eyes
unusual tiredness or weakness

Less common
loss of hearing (temporary)
Pain/redness/swelling at place of injection
irregular or slow heartbeat
Fainting (repeated)

More common
abdominal or stomach discomfort or cramping

vomiting or nausea

Before using Ilosone

It is advised to consult your doctor before you start using Ilosone containing antibiotic agent Erythromycin. Only a medical professional can decide if your condition should be treated with antibiotics. Do not use this medication for common cold or virus infections treatment.ilosone5

If your doctor prescribes you this antibiotic, you should discuss the following things before use:

If you have allergic reactions to antibiotics or other medications;

If you are pregnant or breastfeeding a baby;

If you use other medications;

If you smoke or drink alcohol;

If you have other health issues, including:

·         Heart disease,  irregular heartbeat, a history of heart problems;

·         Liver disease;

·         Loss of hearing or previous history of hearing problems;

·         Kidney disease.

Treatment of bacterial infections in children with this antibiotic should be carefully considered and started only in case the infection is strongly suspected (or proven) to be caused by organisms susceptible to this medication.

Pregnant women should discuss with a doctor the risks and benefits of the use of Ilosone. According to the clinical investigations Erythromycin did not cause any birth defects in unborn babies.

Ilosone pharmacokinetic parameters

The orally applied Ilosone (erythromycin) is quickly absorbed and distributed into most body fluids and tissues. Erythromycin crosses the placenta, and is found in milk. The antibiotic is extensively bound to plasma protein. The max plasma levels are achieved within 1-4 hours post oral dose.

Erythromycin in the medication Ilosone is well absorbed with or without food.  

Erythromycin undergoes the liver metabolism and is eliminated primarily in the bile. The rest of the medication in the unchanged form is excreted in the urine.

Special groups of patients may have altered pharmacokinetic parameters of this medication. The half-life and elimination time may be longer in patients with liver disease.

Ilosone uses

ilosone3Ilosone is indicated to treat a variety of bacterial infections. The medication may be used to prevent streptococcalinfections in patients with rheumatic heart disease who cannot use antibiotics containing penicillin.

Erythromycin is effectively used to treat patients with the following health conditions:

  • Acne
  • Actinomycosis
  • Anthrax
  • Chancroid
  • Gastroparesis
  • Lyme disease
  • Lymphogranuloma venereum
  • Relapsing fever

Ilosone is a prescription medication, consult your doctor before you intend to use this drug.

Ilosone actions

Ilosone contains Erythromycin as a main component. This antibiotic possesses high bacteriostatic characteristics preventing the growth of bacteria in the body. It stops the synthesis of the protein in susceptible bacteria.

In high concentrations Erythromycin becomes bactericidal against susceptible organisms.

The medication has a wide spectrum of activity including gram-positive and -negative bacteria and some other organisms (such as Chlamydia, Mycoplasma, spirochetes).

 Gram-positive bacteria:

·         S. aureus

·         S. pyogenes (group A β-hemolytic streptococci)

·         S. pneumoniae

·         Bacillus anthracis

·         Corynebacterium diphtheriae

·         C. minutissimum

·         Listeria monocytogenes.

Gram-negative bacteria:

·         Bordetella pertussis

·         Legionella pneumophila

·         Moraxella catarrhalis

·         Neisseria gonorrhoeae

·         Enterobacteriaceae (Escherichia coli, Enterobacter, Klebsiella, Proteus, Salmonella, Shigella).

Other organisms:

·         Chlamydia psittaci

·         C. trachomatis

·         Mycoplasma pneumonia

·         Ureoplasma urealyticum

·         Entamoeba histolytica

·         Borrelia burgdorferi

·         Treponema pallidum.

Some infections caused by susceptible bacteria to Erythromycin are treated with this medication in combination with other antibiotics or antibacterial agents. A doctor’s approval and advice is always needed.

Ilosone (Erythromycin)

Ilosone (Erythromycin) is macrolide antibiotic possessing antibacterial properties.

Erythromycin is produced bySaccharopolyspora erythraeus. This antibiotic affects the microbial protein synthesis and stops (and prevents) the growth of bacteria in the body.ilosone

The medication is available in the following dosage forms:

  • Suspension
  • Powder for Suspension
  • Tablet
  • Tablet, Chewable
  • Capsule

The wide spectrum of action of this antibiotic allows using it for a variety of infections caused by bacteria susceptible to this medication.